A SOLITARY HYPERMETABOLIC MEDIASTINAL LESION MIMICKING DISTANT METASTASIS: INSIGHTS FROM SERIAL FDG PET/CT IMAGING
Ahmad Zaid Z. & Shafiq Ayman R.
abstract
This clinical quiz highlights the utilisation and findings of hybrid imaging with fluorodeoxyglucose positron emission tomography/computerised tomography (FDG PET/CT) in an oncology patient with underlying gynaecological cancer. FDG is a glucose analogue and can be used to detect metabolically active tissue. Nevertheless, our patient was found to have a solitary hypermetabolic mediastinal lesion mimicking distant metastasis which has been monitored on serial FDG PET/CT scans.
references
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2. Sergi Juanpere, Noemí Cañete, Pedro Ortuño, et al. (2013). A diagnostic approach to the mediastinal masses. Insights Imaging 4: 29–52.
3. Ravikanth Reddy (2022). Comparative Role of MDCT and FDG-PET/CT in the Diagnostic Evaluation of Mediastinal Mass Lesions: An Institutional Experience. World J Nuclear Med 21: 200–209.
4. Takahiko Nakazono, Charles S. White, Fumio Yamasaki, et al. (2011). MRI Findings of Mediastinal Neurogenic Tumors. AJR 197: W643–W652.
5. CS Wong, Tiffany YC Chu and KF Tam (2010). Retroperitoneal schwannoma: a common tumour in an uncommon site. Hong Kong Med 16: 66-68.
6. Ayako Kamiya, Yukinori Yamagata, Hiroshi Yoshida, et al. (2020). Laparoscopic resection of a primary diaphragmatic schwannoma: a case report and literature review. BMC Surgery 20: 289.
7. Takahiro Tsuchiya, Masako Ikemura, Satoru Miyawaki, et al. (2024). Clinical and radiological features of intracranial ancient schwannomas: a single institution, retrospective analysis. Brain Tumor Pathology 41: 73–79.
8. Rhanim A, El Zanati R, Mahfoud M, et al. (2013). A rare cause of chronic sciatic pain: Schwannoma of the sciatic nerve. J Clin Orthop Trauma 4(2): 89-92.
9. Sylvain Beaulieu, Brian Rubin, David Djang, et al. (2004). Positron Emission Tomography of Schwannomas: Emphasizing Its Potential in Preoperative Planning. AJR 182: 971–974.
10. Paul Boré, Renaud Descourt, Luc Ollivier, et al. (2018). False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma – A Caution for Reporting Physicians. Front. Med 5: 275.
11. Li J, Wang Q, Zhang M, et al. (2021). Malignant Transformation in Vestibular Schwannoma: Clinical Study with Survival Analysis. Front. Oncol 11: 655260.
12. Ali A, Parry A, Halliday D, et al. (2022). Malignant Transformation of a Peripheral Nerve Sheath Tumour in Neurofibromatosis Type 2. Neurosurg Cases Rev 5: 095.
13. Serban O, Poanta LI, Mihaileanu F et al. (2015). Schwannoma of the lower leg with malignant transformation: a case report. EJCRIM 2: Doi: 10.12890/2015_000236.
14. Shen XZ, Wang W, Luo ZY (2021). 18F-FDG PET/CT imaging for aggressive melanotic schwannoma of the L3 spinal root: a case report. Medicine 100: 8 (e24803).